SWOT IT OUT!

Information Technology (IT) and the Healthcare Industry: A SWOT Analysis

The healthcare industry is under pressure to improve patient safety, operate more efficiently, reduce medical errors, and provide secure access to timely information while controlling costs, protecting patient privacy, and complying with legal guidelines. Analysts, practitioners, patients and others have concerns for the industry. Using the popular strategic analysis tool of strengths, weakness...

Sorting it out

The AP-2 adaptor complex is widely viewed as a linchpin molecule in clathrin-mediated endocytosis, simultaneously binding both clathrin and receptors. This dual interaction couples cargo capture with clathrin coat assembly, but it has now been discovered that the association with cargo is tightly regulated. Remarkably, AP-2 is not obligatory for all clathrin-mediated uptake, and several alterna...

Just Out of It

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Desmosomes sort it out

iochemical and kinetic studies have failed to provide a unified view on how the Arp2/3 complex nucleates actin filaments. Does the complex, which mediates actin filament nucleation and branch formation at the leading edge of motile cells, bind to the side of an older actin filament, or does it become incorporated into that filament? B Structural studies now add a new dimension to the discourse,...